Examples of Projects

Selected examples of projects are listed here

Shape-actuating minimally invasive spinal cord stimulator for large-area neuromodulation

This project develops a thin, flexible spinal cord stimulator that can be percutaneously delivered in a tightly rolled form and then pneumatically actuated to expand into a paddle-like geometry over the dorsal cord, enabling large-area epidural neuromodulation through a minimally invasive keyhole approach. It combines soft-film electronics with embedded fluidic channels, validates mechanical, electrochemical, and deployment performance in bench-top assays and human cadaver models, and targets clinical spinal cord stimulation for chronic pain with future extension to motor restoration and other central nervous system indications requiring broad yet low-trauma neural coverage. Read more here.

Electrochemically actuated microelectrode cuffs for minimally invasive peripheral nerve neuromodulation

This project develops electrochemically actuated, ultrathin microelectrode cuffs that can be delivered around peripheral nerves in a low-profile, minimally invasive state and then actively conform to the nerve when a small electrochemical stimulus is applied. It combines soft, stretchable conductors with internal electroactive polymer actuators to generate gentle, controllable radial compression, achieving stable, high-quality neural recording and stimulation while minimizing mechanical trauma and chronic foreign-body response. The targeted applications are peripheral nerve interfaces for bioelectronic medicine, including treatments for inflammatory and metabolic disorders, motor and sensory restoration, and closed-loop neuromodulation therapies that require long-term, high-fidelity access to small-diameter nerves with minimal surgical burden. Read more here.

High-density conformable electrode arrays for body surface potential mapping and non-invasive cardiac electrophysiology

This project develops large-area, soft electrode arrays based on conducting polymer hydrogels that conform intimately to the torso to enable high-density body surface potential mapping with markedly improved spatial resolution and signal quality compared with standard ECG electrodes. It integrates scalable fabrication of hundreds of low-impedance electrodes with flexible wiring and electronics, and validates the platform in human studies, reconstructing detailed epicardial activation maps and arrhythmia substrates from non-invasive measurements. The targeted applications include advanced cardiac diagnostics, such as localization of ectopic foci and characterization of atrial and ventricular arrhythmias, guidance of ablation and device therapy, and longitudinal monitoring of patients with structural or electrical heart disease using a comfortable, wearable mapping system. Read more here.

High-density conformable electrode arrays for body surface potential mapping and non-invasive cardiac electrophysiology

This project develops large-area, soft electrode arrays based on conducting polymer hydrogels that conform intimately to the torso to enable high-density body surface potential mapping with markedly improved spatial resolution and signal quality compared with standard ECG electrodes. It integrates scalable fabrication of hundreds of low-impedance electrodes with flexible wiring and electronics, and validates the platform in human studies, reconstructing detailed epicardial activation maps and arrhythmia substrates from non-invasive measurements. The targeted applications include advanced cardiac diagnostics, such as localization of ectopic foci and characterization of atrial and ventricular arrhythmias, guidance of ablation and device therapy, and longitudinal monitoring of patients with structural or electrical heart disease using a comfortable, wearable mapping system. Read more here.

A conformable organic electronic device for continuous monitoring of epithelial barrier integrity

This project develops a soft, skin-like organic electronic patch that adheres conformally to epithelial tissues and measures transepithelial electrical parameters in situ, enabling non-invasive, real-time assessment of barrier function over large areas. It integrates high-capacitance organic electrodes, flexible encapsulation, and multiplexed readout to track subtle changes in tissue impedance and permselectivity under mechanical deformation, chemical challenge, and wound healing conditions. The targeted applications include early detection and monitoring of skin and mucosal barrier disorders, evaluation of topical and systemic therapies, and longitudinal stratification of patients with chronic inflammatory diseases where epithelial integrity is a key biomarker. Read more here.

Bioelectronic platform for lectin-based enrichment of columnar epithelial cells from minimally invasive capsule samples

This project develops a multiplexed bioelectronic platform that integrates lectin-functionalized electrodes with controlled thermal release to selectively capture and then recover columnar epithelial cells from sponge- or capsule-based esophageal sampling devices. It combines surface-engineered microelectrodes, optimized flow and temperature control, and quantitative imaging to demonstrate high enrichment of target cells from complex clinical-like specimens while preserving nucleic acid integrity for downstream molecular analyses. The targeted applications are early detection and risk stratification of esophageal and other gastrointestinal cancers, enabling scalable, minimally invasive screening programs that couple soft capsule devices with an automated bioelectronic sample preparation module for high-throughput cytology and genomics. Read more here.

Simple dynamic cell culture system to reduce recording noise in microelectrode array measurements

This project develops a straightforward dynamic cell culture setup that gently perfuses media over cells grown on microelectrode arrays, reducing ionic and metabolic gradients that contribute to low-frequency noise in extracellular recordings. It combines a low-cost flow system with standard MEAs and demonstrates that controlled fluid motion substantially improves signal-to-noise ratio without compromising cell viability or requiring complex microfluidics. The targeted applications are higher-fidelity in vitro electrophysiology assays for drug screening and disease modelling, where cleaner recordings enable more reliable detection of subtle changes in neural or cardiac activity using existing MEA platforms. Read more here.

Simple dynamic cell culture system to reduce recording noise in microelectrode array measurements

This project develops a straightforward dynamic cell culture setup that gently perfuses media over cells grown on microelectrode arrays, reducing ionic and metabolic gradients that contribute to low-frequency noise in extracellular recordings. It combines a low-cost flow system with standard MEAs and demonstrates that controlled fluid motion substantially improves signal-to-noise ratio without compromising cell viability or requiring complex microfluidics. The targeted applications are higher-fidelity in vitro electrophysiology assays for drug screening and disease modelling, where cleaner recordings enable more reliable detection of subtle changes in neural or cardiac activity using existing MEA platforms. Read more here.